Table 1. Main characteristics of studies included in the meta-analysis.
| Studies | Country | Ethnicity | Number | Age, year | Male% | Hypertesion% | Smoking% | Diabetes% | hyperlipidemia% | Study type | Primary | Genotype | NOS | HWE test |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (case/control) | (case/control) | (case/control) | (case/control) | (case/control) | (case/control) | (case/control) | outcome | method | score | (control) | ||||
| Gu et al.(2013) | China | Asian | 592/625 | 56.6/55.7 | 60.0/56.0 | 46.8/15.2 | 42.4/14.2 | 33.6/10.2 | NA | Case-control study | CHD | PCR-RFLP | 9 | Yes |
| Luan et al.(2009) | China | Asian | 560/532 | 55.4/55.1 | 73.4/73.3 | 53.8/47.2 | 56.8/36.5 | NA | NA | Case-control study | MI | PCR-RFLP | 9 | Yes |
| Feng et al.(2014) | China | Asian | 84/253 | 55/45 | 78.6/60.1 | 61.9/10.3 | NA | NA | NA | Case-control study | CHD | MassARRAY system | 9 | Yes |
| Csaba et al.(2001) | Hungary | Caucasian | 318/320 | 57.6/58.9 | 76.1/75 | 53.1/0.0 | 66/NA | NA | NA | Case-control study | CHD | PCR-RFLP | 9 | Yes |
| Andrea et al.(2014) | Italy | Caucasian | 200/230 | 57.3/52 | 90.5/42 | 44.9/25 | 69.5/28 | 15.0/3.0 | 74.0/24.0 | Case-control study | MI | PCR-RFLP | 9 | Yes |
| Stavros et al.(2005) | Greece | Caucasian | 208/164 | 63.7/63.2 | 77.6/76.4 | 67.1/54.5 | 57.6/42.4 | 34.3/16.4 | 75.2/59.4 | Case-control study | CHD | PCR-RFLP | 9 | Yes |
| Eleonora et al.(2004) | Germany | Caucasian | 2694/530 | 63.8/56.9 | 73.9/51.3 | 61.9/42.1 | 67.7/46.4 | 22.5/7.5 | 68.4/36.6 | Case-control study | CHD | PCR-RFLP | 9 | Yes |
HWE: Hardy–Weinberg equilibrium; NA: data is not available.