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. Author manuscript; available in PMC: 2015 Jul 2.
Published in final edited form as: Clin Cancer Res. 2013 Dec 18;20(4):1007–1019. doi: 10.1158/1078-0432.CCR-13-1077

Figure 4.

Figure 4

Differences in CD38 and CD200 surface protein and mRNA expression between MALD1 and MCL cases. A, box plots representing the mRNA expression levels of CD38 in the 2 groups, as determined by qRT-PCR and expressed in relative units (Mann–Whitney test). B, box plots depicting the distribution of CD38-positive cells within the clonal peripheral blood B-cell population in the 2 groups (Mann–Whitney test), as assessed by flow cytometry. C, representative examples of flow cytometry analysis of CD38 surface expression in representative MALD1 (top) and MCL (bottom) peripheral blood B cells (CD19+, CD5+, highlighted in red on the right). The mean fluorescence intensity is used as a parameter to plot the levels of CD38 expression (histograms). D, box plot representation of CD200 mRNA total levels in MALD1 and MCL cases and expressed in relative units (Mann–Whitney test). E, box plots depicting the distribution of CD200-positive cells within the clonal peripheral blood B-cell population in the 2 groups (Mann–Whitney test), as assessed by flow cytometry. F, representative examples of flow cytometric analysis of CD200 surface expression in representative MALD1 (top) and MCL (bottom) peripheral blood B cells (highlighted in red) using the mean fluorescence intensity as a parameter (histograms).