Table 5.

Risk of bias table for interrupted time series studies

Study	Was the intervention independent of other changes?	Was the shape of the intervention effect pre-specified?	Was the intervention unlikely to affect data collection?	Was knowledge of the allocated interventions adequately prevented during the study?	Were incomplete outcome data adequately addressed?	Was the study free from selective outcome reporting?	Was the study free from other risks of bias?
Howell et al. [49]	Low risk	Low risk	Low risk	Low risk	Low risk	Low risk	Low risk
Hanson et al. [57]	Low risk	Unclear risk	Low risk	Low risk	Low risk	Low risk	Low risk