Table 3.
Univariate and multivariate analysis of risk factors for RIF resistance in M. tuberculosis complex isolates from retreatment cases around Jimma, Southwest Ethiopia from March 2012 to April 2013 (n = 70)
| Variables | Rifampicin resistance | COR (95 % CI) | p-value | AOR (95 % CI) | p-value | |
|---|---|---|---|---|---|---|
| Yes | No | |||||
| HIV sero-status | ||||||
| Positive | 11 (47.8 %) | 12 (52.2 %) | 2.67 (0.937, 7.63) | 0.066 | 2.89 (0.97, 8.64) | 0.057 |
| Negative | 11 (23.4 %) | 36 (76.6 %) | 1 | 1 | ||
| Retreatment sub-categories | ||||||
| Treatment failure and defaulters | 16 (43.2 %) | 21 (56.8 %) | 2.8 (0.98, 8.15) | 0.054 | 3.04 (1.02, 9.10) | 0.047 |
| Relapse | 7 (21.2 %) | 26 (78.8 %) | 1 | 1 | ||
| Alcohol abuse | ||||||
| Yes | 5 (55.6 %) | 4 (44.4 %) | 2.99 (0.72, 12.42) | 0.143 | 2.89 (0.61, 13.58) | 0.180 |
| No | 18 (29.5 %) | 43 (70.5 %) | 1 | |||
| History of being in prison | ||||||
| Yes | 6 (50 %) | 6 (50 %) | 2.41 (0.68, 5.55) | 0.189** | 1.8 (0.43, 7.57) | 0.421 |
| No | 23 (39.7 %) | 35 (60.3 %) | 1 | 1 | ||
COR Crude Odds Ratio, AOR Adjusted Odds Ratio
**Fisher’s Exact Test p-value