. Author manuscript; available in PMC: 2016 Jun 1.

Published in final edited form as: J Crit Care. 2015 Jan 30;30(3):653.e1–653.e7. doi: 10.1016/j.jcrc.2015.01.017

Table 2.

Association between delirium duration in the ICU and N-back at discharge and at 3 months^a,^b

	Discharge (n = 38)				3 mo (n = 34)

	Coefficient	Lower	Upper	P	Coefficient	Lower	Upper	P
Increased activation
Left inferior parietal	−0.0092	−0.0535	0.0350	.6847	0.0050	−0.0339	0.0438	.8034
Right inferior parietal	−0.0014	−0.0256	0.0227	.9075	0.0239	−0.0417	0.1003	.4249
Left precentral	−0.0031	−0.0526	0.0463	.9016	0.0083	−0.0456	0.0622	.7648
Right middle frontal	−0.0079	−0.0411	0.0252	.6419	0.0155	−0.0498	0.0808	.6447
Left superior parietal	0.0052	−0.0364	0.0260	.7471	−0.0011	−0.0529	0.0507	.9662
Right superior occipital	−0.0019	−0.0238	0.0200	.8674	0.0086	−0.0408	0.0580	.7361
Left middle frontal	−0.0153	−0.0585	0.0879	.4923	0.0018	−0.0723	0.0758	.9630
Right middle frontal	−0.0060	−0.0294	0.0173	.6165	−0.0017	−0.0484	0.0450	.9431
Left supplementary motor area	−0.0043	−0.0335	0.0250	.7767	0.0090	−0.0486	0.0665	.7616
Decreased activation
Superior medial frontal gyrus	0.0002	0.0441	0.0444	.9934	−0.0051	−0.0900	0.8799	.9075
Left posterior cingulate	0.0024	−0.0274	0.0321	.8774	0.0300	−0.0206	0.0806	.2540

Coefficients represent a comparison from the 25th to 75th percentiles of delirium duration (from 0 to 3 days of delirium).

All models are adjusted for age at study enrollment, presence of sepsis at any time during the ICU stay, percent of correct responses to targets on the fMRI N-back test, and mean gray matter volume fraction in the corresponding region.