Fig 4. Selective latex arteriography of an Albumin-Cre/MST1 ^fl/fl /MST2 ^fl/fl mouse that developed multiple spontaneous hepatocellular carcinomas.

(A) Histologic examination (hematoxylin and eosin staining, ×100). (B) The whole liver and (C, D) magnified images from a surgical microscope display a hypervascular mass supplied by feeding arteries (black arrow) and enlarged prominent arteries (white arrow) in the tumor-free background liver. The dotted box in (B) indicates the region magnified in (C, D).