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. 2015 Jun 3;195(2):683–694. doi: 10.4049/jimmunol.1402983

FIGURE 7.

FIGURE 7.

Attenuation of airway inflammation in HDM-treated SPCCre/CARMA3F/F mice. (A) Total cells, macrophages, eosinophils, neutrophils, and lymphocytes were enumerated in BAL fluid. Data are means ± SEM of six to eight mice per group from two experiments. *p < 0.05 (HDM treatment compared with same genotype that was treated with PBS or SPCCre/CARMA3+/+ HDM compared with SPCCre/CARMA3F/F HDM). (B) SPCCre/CARMA3+/+ and SPCCre/CARMA3F/F mice received three doses of HDM followed by 25 μg Alexa Fluor 488–labeled HDM intranasally. Twenty-four hours after Alexa Fluor 488–labeled HDM administration, the lungs and TLNs were isolated and the number of Alexa Fluor 488–labeled HDM+ mDCs were determined by flow cytometry. Data are means ± SEM of six to seven mice per group from one experiment. *p < 0.05.