Figure 3.

Human prioritizer analyses. Novel candidate genes for autism, epilepsy and schizophrenia were predicted by FlyNet, and top-ranked genes were validated using (A) 138 neurological disease genes identified from a recent mutagenesis screen for X-chromosome fly genes and (B) 800 genes with de novo mutations for autism, epilepsy or schizophrenia. The discovery rates for the top 50, 100 and 200 candidates are represented on the bar graph, and the expected discovery rates by random chance are indicated by the dotted lines.