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. 2015 Jul 1;11(7):e1004327. doi: 10.1371/journal.pcbi.1004327

Table 2. Frequency of increased rigidity vs. increased flexibility.

Antibody Chain Flexibility increases a Rigidity increases a
2.3 ≤ < 3.3 3.3 ≤ x -3.3 < ≤ -2.3 x ≤ -3.3
whole FABs
Anti-Fluorescein H 6 19 19 3
L 26 15 23 1
Anti-CD3 H 2 0 20 29
L 16 20 5 3
Esterase catalytic Ab H 2 3 21 37
L 29 38 3 1
Total 81 95 91 74
Complementarity Determining Regions
Anti-Fluorescein H 0 8 5 0
L 11 6 0 0
Anti-CD3 H 0 0 8 11
L 1 3 0 0
Esterase catalytic Ab H 0 0 15 10
L 11 14 0 0
Total 23 31 28 21
CDR H3
Anti-Fluorescein 0 0 5 0
Anti-CD3 0 0 7 3
Esterase catalytic Ab 0 0 7 3
Total 0 0 19 6
CDR L2
Anti-Fluorescein 5 3 0 0
Anti-CD3 4 3 0 0
Esterase catalytic Ab 5 2 0 0
Total 14 8 0 0

a The counts of amino acids belonging to this classification.