TABLE V. LTF haplotype frequencies (and counts) in human immunodeficiency virus (HIV) positive (+) and negative (-) children in the four different populations analysed.
| LTF haplotypes (Thr29Ala-Arg47Lys) | HIV- | HIV+ | HIV- vs. HIV+ (p) |
|---|---|---|---|
| Africa | n = 30 | n = 52 | |
| AG | 0.77 (23) | 0.77 (40) | 1.00 |
| GG | 0.20 (6) | 0.19 (10) | |
| GA | 0.03 (1) | 0.04 (2) | |
| AA | 0.00 (0) | 0.00 (0) | |
| LD (p; D’; r2) | 0.07; 0.99; 0.11 | 0.01; 0.99; 0.13 | - |
| India | n = 62 | n = 90 | |
| AG | 0.47 (29) | 0.39 (35) | 0.56 |
| GG | 0.19 (12) | 0.25 (23) | |
| GA | 0.34 (21) | 0.36 (32) | |
| AA | 0.00 (0) | 0.00 (0) | |
| LD (p; D’; r2) | < 0.01; 0.99; 0.45 | < 0.01; 0.99; 0.35 | - |
| Brazil | n = 70 | n = 156 | |
| AG | 0.46 (32) | 0.51 (79) | 0.19 |
| GA | 0.37 (26) | 0.32 (50) | |
| GG | 0.11 (8) | 0.16 (25) | |
| AA | 0.06 (4) | 0.01 (2) | |
| LD (p; D’; r2) | < 0.01; 0.72; 0.41 | < 0.01; 0.91; 0.45 | - |
| Italy | n = 36 | n = 178 | |
| GA | 0.64 (23) | 0.60 (106) | 0.85 |
| AG | 0.25 (9) | 0.30 (54) | |
| GG | 0.11 (4) | 0.10 (17) | |
| AA | 0.00 (0) | 0.01 (1) | |
| LD (p; D’; r2) | < 0.01; 0.99; 0.59 | < 0.01; 0.97; 0.63 | - |
LD: linkage disequilibrium; LTF: lactoferrin encoding gene.