TABLE. Demographic and clinical characteristics of patients and controls.
| Characteristic | Healthy controls | M-HAV-ILI | I-HAV-ILI |
|---|---|---|---|
| n | 40 | 35 | 36 |
| Mean age (years ± SD) | 6.7 ± 2.5 | 6.5 ± 3.35 | 8.6 ± 4.2 |
| Gender (% female) | 42 | 57 | 51 |
| Mean ALT (UI/L ± SD) | 20.71 ± 12.14 | 533.55 ± 529.82 | 1392.06 ± 1299.90a |
| Mean AST (UI/L ± SD) | 12.4 ± 7.58 | 373.44 ± 357.19 | 1048.72 ± 1189.70b |
| Mean CB (mg/d L± SD) | 0.145 ± 0.094 | 1.02 ± 0.57 | 5.26 ± 2.29 |
| Anti-HAV IgM | - | + | + |
| Anti-HAV IgG | - | - | - |
a: p < 0.001; b: p < 0.05; ALT: alanine aminotransferase; AST: aspartate aminotransferase; CB: conjugated bilirubin; I-HAV-ILI: patients with intermediate hepatitis A virus (HAV)-induced liver injury (CB > 2 mg/dL); M-HAV-ILI: patients with minor HAV-induced liver injury (CB > 0.3 mg/dL - < 2 mg/dL); SD: standard deviation.