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. Author manuscript; available in PMC: 2015 Jul 2.
Published in final edited form as: Matrix Biol. 2011 May 27;30(0):318–329. doi: 10.1016/j.matbio.2011.05.003

Table 1.

Inflammatory responses after cryoinjury.

WT Cav1−/−
sham 3d 14d 30d sham 3d 14d 30d
Infiltrating cell Neutrophil (cells/625μm2) 1.38 ± 0.23 54.3 ± 11.4 1.00 ± 0.25 3.03 ± 0.68 1.05 ± 0.20 59.9 ± 2.5 0.850 ± 0.187 2.35 ± 0.38
Macrophage (cells/625μm2) 4.43 ± 1.89 111 ± 16 64.1 ± 29.0 9.76 ± 3.36 1.32 ± 0.40 98.4 ± 26.7 6.75 ± 3.84 4.10 ± 1.82
Cytokine IL-1β 1 2.38 ± 0.24 0.962 ± 0.202 1.59 ± 0.37 1.52 ± 0.45 1.93 ± 0.48 1.32 ± 0.12 0.869 ± 0.164
IL-6 1 6.38 ±1.23 0.825 ± 0.207 2.85 ± 21 2.39 ± 0.74 11.8 ± 3.5 3.47 ± 0.33 1.95 ± 0.17
TNF-α 1 2.79 ± 0.74 2.92 ± 0.35 1.15 ± 0.23 2.38 ± 0.92 2.17 ± 0.51 1.74 ± 0.15 1.21 ± 0.28
TGF-β 1 0.712 ± 0.012 1.267 ± 0.07 1.27 ± 0.07 1.24 ± 0.10 1.06 ± 0.10 2.14 ± 0.33 1.38 ± 0.12

Upper part:Neutrophils and macrophages were identified by immunohistochemistry in injured WT and Cav1−/− knockout (Cav1−/−) hearts after 3 days, 14 days, and 30 days after cryoinjury. Lower part: Expression of proinflammatory cytokines in the whole heart of WT and Cav1−/− knockout after 3 days, 14 days, and 30 days after cryoinjury.