Fig. 4. Serum M2e antibody responses to swine and avian M2e antigens.
BALB/c mice (N=12) were immunized by MN skin or IM route with M2e5x protein or M2e5x VLPs. Sera were collected at 3 weeks after boost vaccination. The IgG antibody levels were detected using swine M2e or avian M2e peptides as an ELISA coating antigen. (A) Serum IgG antibody responses to swine M2e peptide. (B) Serum IgG antibody responses to avian M2e peptide. Error bars indicate mean ± SEM.