Fig. 7. Mucosal IFN-γ secreting cell spots after viral challenge.

Lung cells were isolated from mice day 4 post-challenge (N=4). IFN-γ secreting cells were detected in the presence of challenged A/Philippines/2/82 (H3N2) virus as a stimulator (2 μg/ml). IFN-γ cytokine-producing cells were counted by ELISPOT reader. Asterisk indicates significant differences (*: <0.05, **: <0.01). Data represent mean ± SEM. IFN: interferon, M2e5x VLP: M2e5x virus-like particle.