TABLE 1.

Relaxivities of DNA–Gd@stars and DNA–Gd@ spheres at 60 and 300 MHz^a

	r1 relaxivity (mM−1 s−1)
	60 MHzb	300 MHzc
ProHance	3.0d	4.0
complex 5	3.8	NM
Gd(III)–DNA	9.5	NM
DNA–Gd@stars/ionic	54.7	9.4
DNA–Gd@stars/particle	108850	19345
DNA–Gd@spheres/ionic	14.6	5.8
DNA–Gd@spheres/particle	8230	3270
DNA–Gd@spheres40nm/ionic	16.8	NM
DNA–Gd@spheres40nm/particle	34520	NM

^a“Ionic” r₁ refers to the contribution of each individual Gd(III) complex to proton relaxation, whereas “particle” describes the product of each particle’s payload and ionic r₁.

^bMeasured at 37 °C in water plus 0.01% Tween 20.

^cMeasured at 25 °C in water plus 0.01% Tween 20.

^dAs previously reported;⁵⁰

NM = not measured.