Table 3. Significant gene expression changes after normal colon tissue-originated DNA treatment in HDFα fibroblasts.

Role in tumorigensis	Gene symbols	References
TLR9 MYD88 pathway	MYD88, IRAK2, TRAF6, NFκB, IL6, IL8, IRF7, IFN-β	[21]
STING/cGAS pathway	ADAR, NFκB, CASP1, CXCL10, IRF7, IFN-β, IL-6	[34]
chemokines	CCRL1, CCL8, CXCL3, CXCL5, CXCL10, CXCL11
fibroblast growth factor	FGF2
apoptosis related genes	CASP7,CFLAR, BCL2
prostaglandines	PTGS2, PTGFR