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. 2015 Jul 2;10(7):e0131116. doi: 10.1371/journal.pone.0131116

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© 2015 Dwivedi et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 7 — Model A: C-C interaction bridges two dimers of HpDprA on DNA and thus allows the protein to oligomerize on DNA. (a)schematic describing the role of C-C interaction restricted to single nucleoprotein filament. (b) outcome of deletion of HpDML1 in nuclease protection assay if model A best represents the role of C-C interactions. Model B: C-C interactions play a role in inter–nucleoprotein filament interaction (c) schematic describing role of C-C interactions in cross interaction of two nucleo–protein filaments. (d)outcome of deletion of HpDML1 in nuclease protection assay if model B best represents the role of C-C interaction. The red colored pie shape indicates ss or dsDNA nuclease. The solid structure represent HpDprA and the black curved line represents ss or dsDNA.