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. 2015 Jul 2;10(7):e0132125. doi: 10.1371/journal.pone.0132125

Table 6. Concordance between manual and automated analysis according to the counting method and the algorithm.

  Retrospective series (Algorithm 1) Prospective series (Algorithm 2)
1p 19q 1p 19q
Manual / Automated Manual / Automated Manual / Automated Manual / Automated
Combination 46/53 (87%) - 0.80 41/53 (77%) - 0.67 42/45 (93%) - 0.85 40/45 (89%) - 0.77
Ratio 43/53 (81%) - 0.69 46/53 (87%) - 0.68 34/45 (76%) - 0.63 32/45 (71%) - 0.58
Combination + Ratio 46/53 (87%) - 0.80 44/53 (83%) - 0.74 41/45 (91%) - 0.77 40/45 (89%) - 0.74
C + R (100 cells) 46/53 (87%) - 0.80 44/53 (83%) - 0.74 41/45 (91%) - 0.77 40/45 (89%) - 0.74
C + R (200 cells) 46/53 (87%) - 0.80  45/53 (85%) - 0.76  45/45 (100%) - 1  45/45 (100%) - 1

Number of cases (%) - Κ coefficient. C + R: Combination + Ratio.