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. 2015 Jul 2;11(7):e1005007. doi: 10.1371/journal.ppat.1005007

Fig 6. PBA restricts intracellular Mtb growth independently of 25(OH)D3.

Fig 6

(A) Intracellular growth of Mtb in MDM treated 4 hrs post-infection with 4mM PBA, 100nM 25(OH)D3 (25D) or co-treatment. (B) Expression of proteinase 3 (PRTN3) in whole blood (WB), PBMC and MN compared to MDM ± Mtb infection ± 25(OH)D3 or co-treatment (Co). (C) Treatment of MDM 4 hrs post-infection in the presence or absence of human neutrophil proteinase 3 (PR3). Median ± IQR (A,C) or Mean ± SD (B); n = 5–10; repeated measures 1-way ANOVA with Bonferroni’s multiple comparisons test (A, B) or Wilcoxon matched-pairs test (C): *, P<0.05; **, P<0.01, ns, non-significant.