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. 2015 Jun 26;8:1581–1588. doi: 10.2147/OTT.S84994

Table 2.

The univariate analysis to evaluate the relationship between clinical variables and OS/PFS

Clinical variables N Median OS (months) 95% CI Log rank (P-value) Median PFS (months) 95% CI Log rank (P-value)
Sex
 Male 96 15.7 13.396–18.004 0.243 9.3 7.380–11.220 0.328
 Female 35 21.9 14.598–29.202 12.9 8.940–16.860
Age
 <65 87 16.2 14.006–18.394 0.128 10.3 8.371–12.229 0.902
 ≥65 44 17.1 5.120–29.080 10.7 5.175–16.225
ECOG PS
 0 38 24.6 21.428–27.772 0.000* 16.1 14.650–17.550 0.000*
 1 49 19.1 16.219–21.981 12.3 9.843–14.757
 2 44 7.1 6.017–8.813 2.9 1.971–3.829
Metastatic sites
 Multiple organs 39 7.7 3.907–11.493 0.004* 2.9 2.043–3.757 0.083
 Viscera# 78 20.4 13.800–27.000 12.3 10.955–13.645
 Lymph nodes 7 16 14.460–17.540 8.8 7.260–10.340
 Bones 7 20.7 16.594–24.806 15.6 9.441–21.759
Previous therapy
 Nephrectomy + immunotherapy 70 22.6 16.769–28.431 0.004* 12.4 9.530–15.270 0.001*
 Immunotherapy alone 25 19.1 11.705–26.495 12.3 9.208–15.392
 Nephrectomy alone 17 6.2 0.000–16.319 5.3 1.220–9.380
 None 19 5.2 1.503–8.897 3.1 2.397–3.803

Notes:

*

P<0.05 was considered as statistically significant.

#

Viscera only consider the lungs and liver, except for other organs.

Abbreviations: CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; OS, overall survival; PFS, progression-free survival.