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. 2015 Jul 2;10(7):e0131392. doi: 10.1371/journal.pone.0131392

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© 2015 Uryash et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — This figure depicts the expression and translocation of Nrf2 transcription factor after 4 wk of daily pGz or no pGz (CONT) (A). pGz significantly increased upregulation of the Antioxidant Response Element transcription factor Nrf2 compared to CONT (*p< 0.01) (B). Translocation of Nrf2 is expressed as the ratio of Nrf2 in nucleus and cytosol. pGz also significantly increased Nrf2 translocation to nucleus compared to CONT (*p< 0.01). Representative Immunoblots of Nrf2 in nucleus and cytosol with respective protein loading controls Anti-Laminin B1 (nucleus) and Anti-α Tubulin (cytosol) in CONT and pGz groups showed increased protein expression of Nrf2 in nucleus of pGz treated mice. Optical Units = O.U.