Fig 1. Doxorubicin is more potent than H₂O₂ at inducing caspase activation.

(A)Representative image showing a Western blot of cleaved caspases 3, 8, and 9 in cell lysates from attached WT MEFs treated with H₂O₂ or doxorubicin at indicated concentrations for 16 h. Equal amount of proteins were loaded. (B-D) Quantitative analysis of immunoreactive bands of cleaved caspases 3, 8, and 9 expressed as fold change relative to WT control. n = 4–6 for each condition. * P < 0.05 vs. control.