. 2015 Mar 19;4(4):e1002720. doi: 10.1080/2162402X.2014.1002720

Table 1.

Summary table of the currently known mechanisms by which the four cytokines act on immune effector cells

	Currently known mechanisms by which the agent acts
Agent	DCs	NK cells	γδ T cells	CD8⁺ T cells
IL-2	Unconfirmed	Telomerase activation¹²¹ Decrease apoptosis¹³³	Reversal of anergy¹³⁸	Decrease apoptosis¹³⁴ Reversal of anergy^138,139
IL-7	Unconfirmed	Decrease apoptosis¹³³	Unconfirmed	Telomerase activation¹²⁵ Decrease apoptosis⁸⁸
IL-21	Induces Apoptosis^107,108	Telomerase activation¹²²	Unconfirmed	Unconfirmed
IL-15	Decrease apoptosis¹³⁶	Decrease apoptosis^130,131	Unconfirmed	Telomerase activation^123–125 Decrease apoptosis¹³²