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Comparison of behavior between BTBR and genetically normal C57bl/6j mice. (a) BTBR mice showed lower levels of direct social engagement (sniffing) both during sociability and social novelty phases of the 3-chamber test compared with C57bl/6j mice. (b) BTBR mice spent more time grooming during each of the phases of the 3-chamber test than their C57bl/6j counterparts. Sample sizes: BTBR, n = 7; C57Bl, n = 6. Data are presented as mean ± SEM. *p < 0.05 vs C57Bl (t test)
