Table 2.
Chi-square (χ2) analysis of PD-L1 expression and TIL density in melanoma brain metastases
| Site of Metastases | PD-L1 (P = 0.31) | CD3TILs (P = 0.01) | CD4TILs (P = 0.09) | CD8TILs (P = 0.01) | ||||
|---|---|---|---|---|---|---|---|---|
| Low | High | Low Density | High Density | Low Density | High Density | Low Density | High Density | |
| Cerebral | 59.1% (13/22) | 40.9% (9/22) | 70.4% (19/27) | 29.6% (8/27) | 73.1% (19/26) | 26.9% (7/26) | 70.4% (19/27) | 29.6% (8/27) |
| Extra-Cerebral | 46.3% (25/54) | 53.7% (29/54) | 43.3% (26/60) | 56.7% (34/60) | 54.1% (33/61) | 45.9% (28/61) | 41% (25/61) | 59% (36/61) |