Table 1.
Demographics, tumor charactitistics and pCR outcome.
| Patient Characteristics by pCR status | Did not attain pCR, N (%)1 | Attained pCR, N (%)2 | P3 |
|---|---|---|---|
|
| |||
| Triple Negativity | |||
| Other (ER+ or PR+ or HER2+) | 17 (77%) | 6 (50%) | 0.10 |
| Triple negative | 5 (23%) | 6 (50%) | |
|
| |||
| Hormone Receptor Status | |||
| ER or PR or both are positive | 16 (73%) | 4 (33%) | 0.026 |
| Both ER and PR are negative | 6 (27%) | 8 (67%) | |
|
| |||
| HER2/Neu status | |||
| Positive | 5 (23%) | 2 (17%) | 0.68 |
| Negative | 17 (77%) | 10 (83%) | |
|
| |||
| Grade | |||
| I, II | 11 (50%) | 3 (25%) | 0.16 |
| III | 11 (50%) | 9 (75%) | |
|
| |||
| Cancer Type | |||
| Ductal Carcinoma | 14 (64%) | 11 (92%) | 0.077 |
| Lobular/Poorly differentiated | 8 (36%) | 1 (8%) | |
|
| |||
| Surgery | |||
| Mastectomy | 18 (82%) | 8 (67%) | 0.32 |
| Lumpectomy | 4 (18%) | 4 (33%) | |
|
| |||
| Race† | |||
| African American | 3 (15%) | 5 (42%) | 0.092 |
| Caucasian | 17 (85%) | 7 (58%) | |
|
| |||
| Age Group | |||
| Under 50 years | 12 (55%) | 6 (50%) | 0.80 |
| 50 years or Older | 10 (45%) | 6 (50%) | |
|
| |||
| BMI Group | |||
| BMI <30 (not obese) | 17 (77%) | 7 (58%) | 0.25 |
| BMI ≥30 (obese) | 5 (23%) | 5 (42%) | |
1
Number and percent of 22 subjects who did not attain pCR.
2
Number and percent of 12 subjects who attained pCR.
3
P values are from two-sided chi-square tests.
†
excluding 1 Hispanic and 1 Asian, both of whom did not attain pCR.