Figure 2. Bacterial counts in the lungs (A) and blood (B) of WT and TNF-α KO mice after intranasal S. pneumoniae infection. The TNF-α KO mice exhibited bacterial counts in the lungs and blood that were significantly increased compared with those in WT mice. Values presented are means±SD. ^*P<0.05 and ^**P<0.01 compared with WT mice.