Table 3.
Sinergistic effect between other non-antibacterial compounds and antifungal drugs.
| Antifungals | Other compounds | Fungal organisms | Reference | Mechanism of synergism |
|---|---|---|---|---|
| Azoles | Chloroquine | C. albicans | Shinde et al. (2013) | Iron deprivation |
| S. cerevisiae | Emerson et al. (2002) | |||
| Ibuprofen | C. albicans | Pina-Vaz et al. (2000) | Efflux pump blocker; increase of azole content | |
| Lactoferrin | Candida sp. | Bellamy et al. (1993) | Direct interaction with the cell surface | |
| Kuipers et al. (1999) | ||||
| Sida Cordifolia compounds | Candida sp. | Ouédraogo et al. (2012) | Immunostimulatory effect | |
| Sertraline | Candida and Cryptococcus sp. | Spitzer et al. (2011) | Alteration of membrane permeability | |
| Statins | Dermatophyte sp. | Nyilasi et al. (2014) | Not described | |
| AMB | Lactoferrin | Candida sp. | Bellamy et al. (1993) | Direct interaction with the cell surface |
| Statins | Dermatophyte sp. | Nyilasi et al. (2014) | Not described | |
| 5-FC | Lactoferrin | Candida sp. | Bellamy et al. (1993) | Direct interaction with the cell surface |
| Nystatin | Sida Cordifolia compounds | Candida sp. | Ouédraogo et al. (2012) | Immunostimulatory effect |
AMB, Amphotericin B; 5-FC, 5-fluorocytosine.