Table 2. Factors associated with survival outcomes in patients with locoregional recurrence.
Variable | DMFS | OS | ||
---|---|---|---|---|
p-value | HR (95% CI) | p-value | HR (95% CI) | |
Adjuvant chemotherapy (yes vs. no) | 0.060 | 0.48 (0.27-0.83) | 0.079 | 0.14 (0.08-0.27) |
DFI (≤ 30 mo vs. > 30 mo) | 0.008 | 2.10 (1.21-3.65) | < 0.001 | 6.96 (3.69-13.12) |
Type of LRR (regional vs. local) | 0.036 | 1.85 (1.04-3.28) | 0.808 | 1.07 (0.62-1.86) |
Tumor size (> 2 cm vs. ≤ 2 cm) | 0.723 | 1.12 (0.60-2.10) | 0.240 | 1.49 (0.77-2.90) |
Nodal status (positive vs. negative) | 0.314 | 1.37 (0.74-2.50) | 0.012 | 2.20 (1.19-4.07) |
DMFS=distant metastasis-free survival; OS=overall survival; HR=hazard ratio; CI=confidence interval; DFI=disease-free interval; LRR=locoregional recurrence.