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. 2015 Jun 23;5(6):e587. doi: 10.1038/tp.2015.77

Figure 4.

Figure 4

Comparison of S1 waveforms, S2 waveforms and S2/S1 ratios during placebo/saline and DMXB-A administration as measured by EEG in a schizophrenia patient (adapted from Olincy et al.25) and an implanted electrode in the CA3 subfield of the DBA/2 mouse hippocampus (adapted from Simosky et al.26). Positive polarity is downwards. Vertical hash marks denote the P50 in the patient and the P20–N40 in the mouse. Similar improvements on sensory gating were observed after DMXB-A treatment in both patients and mice. DMXB-A, 3-2,4 dimethoxybenzylidene anabaseine; EEG, electroencephalography.