Table 1.
Unadjusted Hazard Ratios for Clearance of MRSA Colonization by Baseline Characteristics
| Characteristic | Index Patients, No (%)a | HR (95% CI) | P Value |
|---|---|---|---|
| Age, mean (SD), y | 25.9 (23.3) | 0.99 (.98–.99) | <.001 |
| Age group, y | |||
| <18 | 119 (49.0) | 1.00 (Reference) | Reference |
| 18–44 | 65 (26.8) | 0.68 (.49–.96) | .03 |
| 45–65 | 42 (17.3) | 0.53 (.35–.80) | .002 |
| >65 | 17 (7.0) | 0.68 (.20–.70) | .002 |
| Proportion of household members aged <18 y | … | 1.01 (1.00–1.01) | .02 |
| Female sex | 152 (62.6) | 1.26 (.94–1.69) | .12 |
| Race | |||
| White | 104 (42.8) | 0.61 (.46–.83) | .001 |
| Nonwhite | 139 (57.2) | 1.00 (Reference) | Reference |
| Black/African American | 123 (50.6) | … | … |
| Hispanic | 3 (1.2) | … | … |
| Asian | 3 (1.2) | … | … |
| Mixed/other | 5 (2.1) | … | … |
| Refused to answer | 5 (2.1) | … | … |
| Enrollment site | |||
| HUP | 64 (26.3) | 1.00 (Reference) | Reference |
| CHOP | 105 (43.2) | 1.95 (1.37–2.79) | <.001 |
| HMC | 38 (15.6) | 1.08 (.68–1.71) | .75 |
| PPMC | 34 (12.5) | 1.19 (.73–1.93) | .49 |
| PAH | 5 (2.1) | 0.86 (.27–2.76) | .80 |
| Medical setting | |||
| Emergency department | 167 (68.7) | 1.00 (Reference) | Reference |
| Primary care | 61 (25.1) | 0.92 (.66–1.26) | .59 |
| Inpatient | 15 (6.2) | 0.76 (.42–1.37) | .36 |
| Comorbid conditionb | |||
| Hepatic dysfunction | 12 (5.0) | 0.76 (.39–1.49) | .42 |
| Renal dysfunction | 6 (2.5) | 0.28 (.07–1.13) | .07 |
| Diabetes mellitus | 24 (9.9) | 0.52 (.30–.88) | .01 |
| Cancer | 18 (6.2) | 0.35 (.17–.72) | .004 |
| Organ transplant | 4 (1.7) | 0.43 (.11–1.73) | .23 |
| Prior MRSA infectionc | 53 (29.1) | 0.58 (.40–.83) | .003 |
| Household size, No. of persons | |||
| 1 | 23 (9.5) | 1.00 (Reference) | Reference |
| 2 | 32 (13.2) | 0.72 (.38–1.37) | .32 |
| 3 | 41 (16.9) | 1.15 (.65–2.05) | .63 |
| 4 | 51 (21.0) | 1.42 (.82–2.45) | .21 |
| 5 | 38 (15.6) | 1.02 (.57–1.84) | .95 |
| >5 | 58 (23.9) | 1.40 (.82–2.40) | .22 |
Abbreviations: CHOP, Children's Hospital of Philadelphia; CI, confidence interval; HMC, Penn State Milton S. Hershey Medical Center; HR, hazard ratio; HUP, Hospital of the University of Pennsylvania; MRSA, methicillin-resistant Staphylococcus aureus; PAH, Pennsylvania Hospital; PPMC, Penn Presbyterian Medical Center; SD, standard deviation.
a Data represent No. (%) unless otherwise specified.
b Proportion calculated using available data (available for 242 index patients).
c Proportion calculated using available data (available for 182 index patients).