Table 1. Identification of cell mass in pig subretinal space.
| Antibody | Cell Specifity | Test results in cell mass | Test results in pig tissue (4% FPA) |
||||
|---|---|---|---|---|---|---|---|
| Brain | Liver | Lung | Spleen | Heart | |||
| Nestin | Neural stem cell marker | − | − | − | − | +++ | − |
| Ki67 | Cellular proliferation marker | − | + | ++ | +++ | ++++ | ++ |
| PCNA | Proliferating cell nuclear | − | − | − | − | +++ | − |
| CD45 | Monocyte, leukocyte | + | − | − | − | +++ | − |
| Macrophage | CD68 | + | − | − | − | +++ | − |
| GFAP | Astrocyte | − | ++ | − | − | − | − |
| IgG | IgG-Fc Fragment | + | NT | NT | NT | ++++ | NT |
NT =not tested. The intensity of positive labeling was assessed as + to ++++. − mean no immunolabeling seen.