. 2015 Jul 3;5:11820. doi: 10.1038/srep11820

Table 1. Sterile protection and median delay induced by ChAd63-MVA P. falciparum vaccines in inbred and outbred mice.

Vaccine	BALB/c	Median delay^b	CD-1	Median delay^b
Vaccine	Protection (%)^a	Median delay^b	Protection (%)^a	Median delay^b
PfCSP	37.5****	1.47***	33.3**	0.48*
PfTRAP	0	−0.06	30*	0.03
PfLSAP1	0	0.05	30	0
PfETRAMP5	0	0.12	10	0
PfCelTOS	0	−0.25*	0	0.28
PfUIS3	12.5***	1.42**	0	1.1
PfLSAP2	87.5****	1.09	70***	0.29
PfFalstatin	0	0.59**	10****	0.97****
PfLSA1	87.5****	2.13	87.5****	2
PfLSA3^c	12.5*	0.35*	0	0.22

^aPercentage of vaccinated mice that were sterilely protected from challenge with 1000 chimeric sporozoites i.v., n = 8–10.

^bThe median delay (days) in time to 1% parasitaemia, calculated by: (time to 1% of vaccinee) – (average time to 1% of naïve controls). The difference in survival was generated using Kaplan-Meier survival curves with statistical significance assessed using the Log-Rank (Mantel-Cox) Test, *p < 0.05-0.01 **p < 0.01-0.001 ***p < 0.001 ****p < 0.0001.

^cFor PfLSA3 challenge, the chimeric sporozoite dose was increased to 2000 sporozoites per mouse in order to infect all naïve controls.