Table 1.
Correlation between PAK1 overexpression and clinicopathological variables in primary esophageal small cell carcinoma.
| Clinical Variables | Total Number | PAK1 Overexpression | ||
|---|---|---|---|---|
| Negative | Positive | p Value | ||
| Gender | ||||
| Male | 24 | 7 | 17 | 0.271 |
| Female | 10 | 5 | 5 | |
| Age (Years) | ||||
| <60 | 18 | 9 | 9 | 0.080 |
| >60 | 16 | 3 | 13 | |
| Location of tumors | ||||
| Upper third of esophagus | 5 | 4 | 1 | 0.011 |
| Middle third of esophagus | 22 | 4 | 18 | |
| Lower third of esophagus | 7 | 4 | 3 | |
| Depth of tumors | ||||
| T1/T2 | 16 | 8 | 8 | 0.151 |
| T3/T4 | 18 | 4 | 14 | |
| Lymph node metastasis | ||||
| Without lymph node metastasis | 11 | 7 | 4 | 0.026 |
| With lymph node metastasis | 23 | 5 | 18 | |
| Immunohistochemistry | ||||
| PAK1 overexpression in PESCC | 34 | 12 | 22 | 0.000 |
| PAK1 overexpression in ANCT | 18 | 16 | 2 | |
The correlation between the expression level of PAK1 and different clinical variables was calculated by Fisher’s exact test or χ2 test whichever is appropriate. p value <0.05 is considered statistically significant; PESCC—Primary esophageal small cell carcinoma; ANCT—Adjacent non-cancerous tissue.