Table 3.
Group | Number of Hits/Size of Dataset | EF | |||||
---|---|---|---|---|---|---|---|
Decoy Set | Decoys | Inhibitors | 1% | 2% | 5% | 10% | |
1 | 2063/2804 | 2012/2750 | 51/54 | 11.56 | 7.89 | 5.50 | 3.34 |
2 | 836/915 | 820/899 | 16/16 | 26.13 | 18.44 | 11.20 | 6.84 |
3 | 1048/1121 | 1019/1092 | 29/29 | 14.46 | 10.33 | 8.34 | 6.54 |
4 | 629/716 | 586/673 | 43/43 | 14.63 | 14.63 | 12.74 | 8.59 |
5 | 737/773 | 728/764 | 9/9 | 0.00 | 10.92 | 6.64 | 3.32 |
6 | 93/109 | 77/93 | 16/16 | 5.81 | 5.81 | 4.65 | 3.49 |
7 | 542/593 | 519/570 | 23/23 | 23.57 | 17.14 | 9.60 | 4.80 |
8 | 585/866 | 543/824 | 42/42 | 9.29 | 4.64 | 2.40 | 2.60 |
Total | 6533/7897 | 6304/7665 | 229/232 | 10.09 | 7.84 | 5.06 | 3.15 |