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BDDPM inhibits Vessel Sprouting in HUVECs. HUVECs spheroids were seeded in the Matrigel with or without BDDPM. (A) After 24 h incubation, the sprouting spheroids were photographed (200× magnification); (B,C) The number of primary sprouts and the total sprout length were analyzed. The data shown in the graphs are the mean ± SD values of at least three individual experiments. * p < 0.05, ** p < 0.01 versus control.
