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. 2015 Jun 19;16(6):14098–14108. doi: 10.3390/ijms160614098

Figure 1.

Figure 1

Expression ratios of differentially expressed microRNAs in the serum of dogs with myxomatous mitral valve disease (MMVD). Groups of six dogs each included normal dogs at risk of heart disease (Stage A), asymptomatic dogs with MMVD and mild to moderate cardiac enlargement (Stage B1/B2) and dogs with MMVD and congestive heart failure requiring multiple cardiac medications (Stage C/D). (A) shows miRNAs upregulated in dogs with stage B1/B2 or stage C/D compared to stage A; and (B) shows miRNAs downregulated in dogs with stage B1/B2 or stage C/D compared to stage A. Blue bars indicate the changes in stage B1/B2 and red bars indicate the changes in stage C/D, compared to stage A.