Table 1.
Characteristics of the Mayo Clinic Biobank participants, for all and two HRQOL-related domains
| Overall cohort (n = 21,736) | Perceived general health | Depressive symptoms | |||||
|---|---|---|---|---|---|---|---|
| Deficits (n = 2079) | Non-deficits (n = 19,657) | P-value* | Deficits (n = 1009) | Non-deficits (n = 20,727) | P-value** | ||
| Age, | <0.001 | <0.001 | |||||
| Median (25th – 75th % tiles) | 62 (52,72) | 63 (52,74) | 62 (52,74) | 55 (45,66) | 63 (52,72) | ||
| Female % | 57 % | 58 % | 57 % | 0.52 | 61 % | 57 % | 0.03 |
| Education | <0.001 | <0.001 | |||||
| High school or less | 18 % | 28 % | 17 % | 24 % | 18 % | ||
| Some college | 33 % | 40 % | 32 % | 40 % | 33 % | ||
| Bachelor degree | 25 % | 16 % | 26 % | 17 % | 25 % | ||
| Graduate school | 24 % | 16 % | 25 % | 19 % | 24 % | ||
| Employment | <0.001 | <0.001 | |||||
| Not working - retired | 34 % | 41 % | 33 % | 25 % | 34 % | ||
| Not working - others | 12 % | 29 % | 10 % | 30 % | 11 % | ||
| Currently working | 54 % | 30 % | 56 % | 44 % | 54 % | ||
| BMI | <0.001 | <0.001 | |||||
| Underweight | 2.0 % | 3.6 % | 1.8 % | 3.3 % | 2.0 % | ||
| Normal | 28 % | 24 % | 29 % | 25 % | 28 % | ||
| Overweight | 37 % | 26 % | 37 % | 28 % | 37 % | ||
| Obese | 33 % | 47 % | 32 % | 43 % | 33 % | ||
| Smoking, ever % | 42 % | 54 % | 41 % | <0.001 | 54 % | 42 % | <0.001 |
| Alcohol | <0.001 | <0.001 | |||||
| Never or less than once a month | 42 % | 64 % | 39 % | 57 % | 41 % | ||
| Once a week or less | 23 % | 17 % | 24 % | 19 % | 23 % | ||
| 2+ a week | 35 % | 19 % | 37 % | 24 % | 36 % | ||
| Disease burden (Number of self-reported diseases), | <0.001 | <0.001 | |||||
| Median (25th – 75th % tiles) | 4 (2,6) | 8 (5,10) | 4 (2,6) | 6 (4,9) | 4 (2,6) | ||
*, **P-values comparing subjects with and without deficits in perceived general health (*), and depressive symptoms (**)