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. 2015 Jul 4;13:212. doi: 10.1186/s12967-015-0568-z

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© Kalyan et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Systemic gene expression levels of RANK and AHR explain part of the variation observed in the oral microbiome. Ordinations of all microbial communities are plotted using principal coordinates analysis (capscale) based on Bray-Curtis dissimilarities. The contour of RANK (upper panel) and AHR (lower panel) gene expression levels are average values calculated using a multi-dimensional linear model in odisurf, and arrows indicate the direction of increasing gene expression.