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. 2015 May 21;14:47. doi: 10.1186/s12944-015-0046-x

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© Xia et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Significant brain functional connectivity to the bilateral hippocampus using one-sample t-test: (a1) left hippocampal functional connectivity for healthy controls; (a2) left hippocampal functional connectivity for T2DM patients with target cholesterol; (a3) left hippocampal functional connectivity for T2DM patients with poorly controlled cholesterol; (b1) right hippocampal functional connectivity for healthy controls; (b2) right hippocampal functional connectivity for T2DM patients with target cholesterol; and (b3) right hippocampal functional connectivity for T2DM patients with poorly controlled cholesterol. Thresholds were set at a corrected p < 0.05, determined by Monte Carlo simulation. The left side corresponds to the right hemisphere of the brain