Stress |
Chronic |
Role and environmental stress, neighborhood security, discrimination
|
Wheaton Chronic Stress (WCS) Scale, Lifetime Discrimination Scale, Neighborhood Safety and Violence Scale [70–72] |
Major events |
Lifetime & recent exposure to major life events and trauma (e.g., bereavement, abuse)
|
Lifetime Adversity and Recent Life Event subscales of WCS [70] |
Subjective |
Perceived stressfulness of life over last month
|
Perceived Stress Scale [73] |
Daily events |
Exposure to daily hassles and stressors (e.g., arguments, deadlines, illness)
|
Adapted from Daily Inventory of Stressful Experiences [74] |
URT |
Event-related |
Recurring thoughts about major stressor
|
Impact of Events Scale-Revised [75] |
Dispositional |
Tendency to ruminate or reflect
|
Rumination-Reflection Questionnaire [38]; White Bear Suppression Inventory [37] |
Momentary |
Experiencing recurring, unwanted, negative thoughts
|
Momentary Thought Questionnaire |
Cognition |
Laboratory |
Working memory
|
Operation-span, Counting-span, Backward letter span |
episodic memory
|
AVLT, Paired-associates, Card Memory Task |
processing speed
|
Letter, Number and Symbol matching |
fluid and crystallized intelligence
|
Ravens Progressive Matrices; Vocabulary |
|
Ambulatory |
Working memory (verbal, spatial), processing speed
|
See Fig. 2
|
Biomarkers |
Laboratory |
Basal inflammatory markers
|
Plasma cytokines: IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, TNF-α, IFN-γ, GM-CSF; Plasma CRP |
Ambulatory |
LPS-stimulated cytokines
|
Plasma cytokines: IL-1β, IL-6, IL-8, IL-10, TNF-α, GM-CSF |
Stress-related hormones
|
Salivary cortisol sampled 4 times per day for the first 5 days of each burst |
Plasma cortisol; Plasma DHEAS |
Physical & Mental Health |
Objective |
Metabolic risk indicators
|
Lipid profiles; insulin; glucose |
|
Subjective |
Physical functioning, medical history, medication use, anxiety, depression, mood over last month, life satisfaction
|
PROMIS Physical Function Short Form-A, PROMIS Emotional Distress – Anxiety – Short Form 7-A, PROMIS Depression Short From 8-A, Positive and Negative Affect Schedule, Satisfaction with Life Scale [64, 76, 77] |
Risk & Protective Factors |
Risk |
Neuroticism, social isolation, childhood adversity, anger
|
International Personality Item Pool (IPIP) Neuroticism subscale, PROMIS Social Isolation – Short Form-6a, Childhood Adversity subscale from WCS, State-Trait Anger Expression Inventory [70, 78, 79] |
|
Protective |
Conscientiousness, social support, positive events, optimism, adult temperament, mindfulness
|
IPIP Conscientiousness subscale, PROMIS Emotional, Informational, and Instrumental Social Support – Short Forms-6a, Pleasant Events Schedule, Life Orientation Test, Adult Temperament Questionnaire, Five Facet Mindfulness Questionnaire [64, 78, 80–83] |
Demographics |
Person |
Age, race, ethnicity, gender
|
Demographic questionnaire |
|
Context |
income, work status, marital status, education
|
|