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. 2015 Jun 1;5(5):312–320. doi: 10.1089/brain.2014.0334

FIG. 1.

FIG. 1.

Mean functional connectivity maps of the seed regions in the vACC (1a), amygdala left (2a), OFC left (3a), vACC right (4), amygdala right (5), orbitofrontal cortex right (6), and the PCC (7) (green, NF1 patients; yellow, controls; pink, the seed). Group differences are shown in (1b, 2b, and 3b). In NF1 patients, areas show positive coupling in functional connectivity with the vACC left (1b) and the amygdala left (2b, red), and negative coupling with the amygdala left (2b, blue) and the orbitofrontal cortex left (3b, blue) when compared to controls. No differences in functional connectivity were found for right hemispheric seeds or for the PCC (corrected p=0.05, z=2.3). NF1, neurofibromatosis type 1; vACC, ventral anterior cingulate cortex; OFC, orbitofrontal cortex; PCC, posterior cingulate cortex.