Table 3.
Biopsy site and proportion of subjects with E. coli-laden macrophages
| Subject group | CD | UC | Healthy controls |
|---|---|---|---|
| Subject numbers | 35 | 9 | 18 |
| Biopsy site | |||
| rectum | 11 | 9 | 18 |
| colon (other) | 9 | - | - |
| ileum | 14 | - | - |
| jejunum | 1 | - | - |
| Total | 25/35 (71 %) (71 %)((71 %) | 1/9 (11 %) | 0/18 (0 %) |
| According to histological severity | |||
| normal | 3/7 | 0/0 | 0/18 |
| mild | 20/26 | 0/8 | - |
| moderate | 2/2 | 1/1 | - |
| severe | 0 | 0/0 | - |
| According to endoscopic severity score | |||
| CD patients | |||
| SES-CD (biopsied segment) | |||
| 0 | 0/3 | ||
| 1-2 | - | ||
| 3 | 6/11 | ||
| 4 | 13/15 | ||
| 5-7 | 6/6 | ||
| >7 | - | ||
| SES-CD (total score) | |||
| 0 | 0/3 | ||
| 1-2 | - | ||
| 3-4 | 8/14 | ||
| 5-8 | 9/10 | ||
| 9-13 | 7/7 | ||
| >13 | - | ||
| UC patients | |||
| Modified Baron score | |||
| 0 | - | ||
| 1 | 0/8 | ||
| 2 | 1/1 | ||
| 3 | - | ||
patient with jejunal CD - SES-CD total not recorded as no colonoscopy
HC healthy controls; UC ulcerative colitis; CD Crohn’s disease