Table 3.

Stem cell transplantation procedures

Patient	Age at 1st BMT	Type of BMT			HLA Match	Conditioning			GVHD Prophylaxis
		1st HSCT	2nd HSCT	3rd HSCT		1st HSCT	2nd HSCT	3rd HSCT
1	35 d	MRD, BM	MRD, BM, Same donor		9/10	Flu 16mg/kg	Flu 150mg/m2, Cam 0.8mg/kg, Melf 140mg/m2		Tacrolimus
2	23 m	MRD, PBSC, CD34+			9/10	Flu 150mg/m2, Bu 140mg/m2, ATG 12.5mg/kg			Prednisone
3	8m	MMRD, PBSC, CD34+			Haplo 3/6	Flu 150mg/m2, Melf 280/m2, ATG 12.5mg/kg			none
4	4m	MMRD, PBSC, CD2−/CD8−			Haplo 3/6	None			Prednisone
5	6 m	MMRD, PBSC, CD34+ CD3−	MMRD, PBSC, CD34+/CD3−, Cryopreserved, Same donor	MMRD, BM, CD3-−/CD19−, Same donor	Haplo 5/10	Bu 16mg/kg, Flu 160mg/m2, ATG 10mg 1kg			CyA
6	12m	MMRD, PBSC	MMRD, PBSC Same donor		Haplo 3/6	Flu4mg/kg, Cam 24mg	Bu 16mg/kg, Flu 4mg/kg, Cam 24 mg		MTX, Tacrolimus (2nd HSCT)
7	14m	MMRD, BM S+E Maternal	MMRD, BM S+E Paternal	MMRD, BM S+E Paternal	Haplo 3/6	ATG 30mg/kg	ATG 80mg/kg, Cyclo 100mg/kg	ATG 80mg, Cyclo 120mg/kg, TBI	None
8	2 m	MMRD, BM S+E	MMRD, BM, S+E same donor		Haplo 3/6	Cyclo 200mg/kg ATG 80mg/kg			None
9	16 m	MUD, BM			6/6	Bu 16mg/kg, Cyclo200mg/kg			Prednisone, CyA
10	4 m	MUD, BM			6/6	Bu 16mg/kg, Cyclo 200mg/kg			Prednisone, CyA
11	4 m	MUD, BM			9/10	Bu 16mg/kg, Cyclo 200mg/kg			Prednisone, CyA
12	1m	MMUD, Cord			4/6	None			MTX, Tacrolimus
13	25 d	MUD, Cord			6/6, 10/10	None			MTX, Tacrolimus

ATG: Anti Thymocyte Globulin; BM: Bone Marrow; Bu: Busulfan; Cam: Campath; CyA: Cyclosporine A; Cyclo: Cyclophophomide; Flu: Fludarabine; HI: Haploidentical; Melf: Melfalane; MTX: Methotrexate; MRD: Matched Related Donor (matched was defined as 9/10 antigen or better); MUD: Matched Unrelated donor; MMRD: Mismatched Related Donor; MMUD: Mismatch Unrelated Donor; PBL: Peripheral Blood; PBSC: Peripheral Blood Stem Cell; TBI: Total body radiation; S+E: Soybean agglutinin and sheep erythrocyte rosettting.