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. Author manuscript; available in PMC: 2015 Jul 3.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2012 Sep 27;32(12):2839–2846. doi: 10.1161/ATVBAHA.112.300345

Figure 3.

Figure 3

High-fat diet− (HFD) fed nuclear factor– (erythroid-derived 2) like 2 factor−deficient (Nrf2−/−) bone marrow transplant (BMT) mice reveal enhanced proatherosclerotic gene expression in comparison with wild-type (WT) BMT mice. Expression of (A) antioxidant genes, (B) proinflammatory genes, and (C) Cd36. (Mean±SEM, n=4–9/group; *P<0.05, ***P<0.005 and 0.05>°P<0.1 (trend) vs. WT for matched diet, †P<0.05, ††P<0.01, †††P<0.005 vs. chow for matched genotype). Nqo1 indicates NAD(P)H dehydrogenase, quinone 1; Gpx4, glutathione peroxidase 4; KO, knockout; Mcp1, monocyte chemoattractant protein-1; Tnf, transforming growth factor; OPN, osteopontin.