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. Author manuscript; available in PMC: 2016 Jul 3.
Published in final edited form as: Circ Res. 2015 May 11;117(2):178–191. doi: 10.1161/CIRCRESAHA.117.305853

Figure 1. Pro-inflammatory markers are elevated in the bone marrow (BM) of two rat models of hypertension.

Figure 1

A. BM mononuclear cells (MNCs) from the SHR show increased mRNAs for CCL2, CSF2, IFNγ, and IL1β compared to WKY (n=4 per group). *p < 0.05 vs WKY. B. CCL2 levels are elevated in SHR BM supernatant, serum, and cerebrospinal fluid (CSF) (n=4 per group). *p < 0.05, **p < 0.01 vs WKY; & p < 0.05 vs serum. C. BM MNCs from chronic Ang II infusion in SD rats have increased mRNA of CCL2, CCR2, Hif1α, IL1β, Nos2, TLR4, and TNFα compared to saline-infused SD control rats (n=6 per group). *p < 0.05 vs control.