Figure 2. Bone marrow (BM) reconstitution modulates blood pressure and autonomic function in SHR and WKY rats.
A. Mean arterial pressure (MAP) was measured directly by radiotelemetry (n=5 per group). Reconstitution of the WKY rat with SHR bone marrow increases MAP. Conversely, reconstitution of the SHR with WKY bone marrow lowers MAP. B. Spectral analysis of the systolic blood pressure (SBP) and pulse interval (PI) waveforms of telemetry (n=5 per group). sBRG: spontaneous baroreflex gain, LF: low frequency, VLF: very low frequency. C. Plasma norepinephrine (NE) is elevated in the WKY-SHR vs WKY-WKY. There is no change in the SHR rats with WKY bone marrow (n=5 per group). *p < 0.05, **p < 0.01 vs WKY-WKY; #p < 0.05, ##p < 0.01 vs SHR-SHR.