Table 1.
Characteristics of controls and cases with colorectal cancer (CRC), stratified by sex
| Women | Men | |||||
|---|---|---|---|---|---|---|
| Variable | Controls n=5747 |
CRC n=5644 |
P a | Controls n=4539 |
CRC n=4582 |
P a |
| Smoking status | <0.001 | <0.001 | ||||
| Never | 3029 (52.9) | 2819 (50.2) | 1706 (37.9) | 1525 (33.6) | ||
| Former | 2145 (37.4) | 2126 (37.9) | 2365 (52.6) | 2422 (53.3) | ||
| Current | 554 (9.7) | 669 (11.9) | 428 (9.5) | 594 (13.1) | ||
| Missing | 19 | 30 | 40 | 41 | ||
| Body mass index (kg/m2) | <0.001 | <0.001 | ||||
| <25 | 2699 (47.0) | 2347 (41.6) | 1637 (36.1) | 1324 (28.9) | ||
| 25–29.99 | 1935 (33.7) | 1964 (34.8) | 2223 (49.0) | 2344 (51.2) | ||
| ≥30 | 1113 (19.4) | 1333 (23.6) | 679 (15.0) | 914 (19.9) | ||
| Family history | <0.001 | <0.001 | ||||
| No | 4806 (86.0) | 4483 (82.0) | 3685 (89.9) | 3430 (82.1) | ||
| Yes | 782 (14.0) | 986 (18.0) | 414 (10.1) | 749 (17.9) | ||
| Missing | 159 | 175 | 440 | 403 | ||
| Diabetes | <0.001 | 0.01 | ||||
| No | 4742 (95.0) | 4362 (91.1) | 3262 (91.0) | 3289 (89.2) | ||
| Yes | 249 (5.0) | 428 (8.9) | 323 (9.0) | 400 (10.8) | ||
| Missing | 756 | 854 | 954 | 893 | ||
| Aspirin/NSAID use | <0.001 | <0.001 | ||||
| No | 3553 (62.0) | 3895 (69.3) | 2519 (55.7) | 2928 (64.3) | ||
| Yes | 2176 (38.0) | 1727 (30.7) | 2004 (44.3) | 1626 (35.7) | ||
| Missing | 18 | 22 | 16 | 28 | ||
| Fruit (servings/day) | <0.001 | 0.01 | ||||
| Q1 | 1052 (19.1) | 1072 (20.3) | 780 (18.0) | 824 (19.6) | ||
| Q2 | 2101 (38.2) | 2226 (42.1) | 1905 (43.9) | 1917 (45.7) | ||
| Q3 | 1397 (25.4) | 1204 (22.7) | 982 (22.6) | 888 (21.2) | ||
| Q4 | 952 (17.3) | 790 (14.9) | 673 (15.5) | 566 (13.5) | ||
| Missing | 245 | 352 | 199 | 387 | ||
| Vegetables (servings/day) | <0.001 | <0.001 | ||||
| Q1 | 1222 (22.2) | 1328 (24.9) | 805 (18.5) | 863 (20.5) | ||
| Q2 | 1825 (33.1) | 1824 (34.3) | 1791 (41.1) | 1832 (43.5) | ||
| Q3 | 1394 (25.3) | 1209 (22.7) | 1086 (24.9) | 893 (21.2) | ||
| Q4 | 1071 (19.4) | 962 (18.1) | 673 (15.5) | 623 (14.8) | ||
| Missing | 235 | 321 | 184 | 371 | ||
| Processed meat (servings/day) | <0.001 | <0.001 | ||||
| Q1 | 893 (19.1) | 787 (19.0) | 837 (23.4) | 634 (18.6) | ||
| Q2 | 1914 (41.0) | 1514 (36.4) | 1413 (39.5) | 1281 (37.6) | ||
| Q3 | 1117 (23.9) | 1108 (26.7) | 698 (19.5) | 780 (22.9) | ||
| Q4 | 742 (15.9) | 745 (17.9) | 630 (17.6) | 714 (20.9) | ||
| Missing | 1081 | 1490 | 961 | 1173 | ||
| Red meat (servings/day) | 0.001 | <0.001 | ||||
| Q1 | 1489 (26.8) | 1235 (23.7) | 1228 (28.2) | 949 (22.9) | ||
| Q2 | 1439 (25.9) | 1378 (26.4) | 1325 (30.4) | 1177 (28.4) | ||
| Q3 | 1421 (25.6) | 1371 (26.3) | 1009 (23.1) | 1077 (26.0) | ||
| Q4 | 1207 (21.7) | 1232 (23.6) | 798 (18.3) | 940 (22.7) | ||
| Missing | 191 | 428 | 179 | 439 | ||
| Menopause hormone therapy | <0.001 | - | ||||
| No | 3062 (58.9) | 3334 (67.6) | - | - | ||
| Yes | 2139 (41.1) | 1599 (32.4) | - | - | ||
| Missing | 546 | 711 | - | - | ||
NSAID, non-steroidal anti-inflammatory drug.
a
P-value from Chi-square tests for categorical variables. Missing categories were excluded from comparison tests.