Effects of Propranolol (PRO) on direct DA agonist-induced ALO AIMs (A,C) and rotations (B,D). Five min after pretreatments with Vehicle (VEH) or PRO (5 or 20 mg/kg, ip), rats (n=9) received treatments with either the D1 receptor (D1R) agonist SKF81297 (SKF; 0.08 mg/kg, sc) or the D2 receptor (D2R) agonist Quinpirole (Quin; 0.05mg/kg, sc). Symbols demonstrate median ALO AIMs ± median absolute deviations (M.A.D.) and mean rotations ± standard error of the mean (S.E.M.) every 10 min over the 3 h sampling period immediately after SKF or Quin. For the inset graphs in panels, bars denote the median ALO AIMs + M.A.D. and mean rotations + S.E.M. for the entire 3 h period after SKF or Quin.