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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Mol Nutr Food Res. 2015 Mar 16;59(7):1373–1383. doi: 10.1002/mnfr.201400734

Figure 1.

Figure 1

Interactions between FADS1 rs174548 and rs174538 and dietary fatty acids for circulating omega-3 fatty acids, in each cohort. In ARIC, CARDIA, CHS, InCHIANTI and MESA, fatty acids were measured in plasma/plasma phospholipids; in GOLDN, HPFS, NHS and WGHS, fatty acids were measured in erythrocyte membranes. Panel A illustrates the association of each one gram/day greater intake of dietary alpha linoleic acid (ALA) with circulating docosapentaenoic acid (DPA) per copy of the rs174548 G allele. Panel B illustrates the association of each one gram/day greater intake dietary linoleic acid (LA) with circulating docosahexaenoic (DHA) per copy of the rs174538 A allele. Circulating DPA was not measured in the InCHIANTI study.